Storthyngura spinosissima n. sp. is described from material obtained from the Weddell Sea, south of Vestkapp and in the Drake Passage, at a depth of 417-1681 m. The new species is most similar to S. praegrandis George & Menzies, 1968, but differs in the following details: the dorsum of S. spinosissima n. sp. is covered by numerous small spine-like tubercles and short, hairlike setules, which are absent in S. praegrandis; the tubercles of the latter are less numerous; the interantennular space of S. spinosissima n. sp. is narrower than in S. praegrandis; the antennula of S. spinosissima n. sp. bears a less pronounced distomedial spine on the first peduncular article; and the uropodal endopods are slightly shorter and the exopods less wide in S. spinosissima n. sp. than in S. praegrandis.